Masataka Nakamura Selected Research

Prostaglandin D2

12/2020	Niacin ameliorates ulcerative colitis via prostaglandin D2 -mediated D prostanoid receptor 1 activation.
1/2019	Epithelial cell-derived prostaglandin D2 inhibits chronic allergic lung inflammation in mice.
1/2017	Mast cell-derived prostaglandin D2 attenuates anaphylactic reactions in mice.
1/2017	Niacin ameliorates ulcerative colitis via prostaglandin D2-mediated D prostanoid receptor 1 activation.
11/2016	Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction.
12/2014	A deficiency in the prostaglandin D2 receptor CRTH2 exacerbates adjuvant-induced joint inflammation.
1/2014	Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation.
3/2013	Anti-inflammatory role of PGD2 in acute lung inflammation and therapeutic application of its signal enhancement.
10/2011	Distinct roles of prostaglandin D2 receptors in chronic skin inflammation.
7/2011	Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.

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Masataka Nakamura Research Topics

Disease

17	Septic Shock (Toxic Shock Syndrome) 01/2014 - 06/2002
17	Sepsis (Septicemia) 01/2013 - 01/2004
12	Inflammation (Inflammations) 01/2019 - 08/2003
9	Neoplasms (Cancer) 07/2021 - 11/2005
7	Critical Illness (Critically Ill) 01/2010 - 01/2004
6	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2018 - 03/2008
6	Infections 10/2017 - 07/2003
6	Cytokine Release Syndrome 12/2012 - 01/2004
4	Pneumonia (Pneumonitis) 01/2019 - 02/2006
4	Hypersensitivity (Allergy) 04/2016 - 03/2006
3	Arthritis (Polyarthritis) 12/2014 - 04/2009
3	Contact Dermatitis (Eczema, Contact) 10/2011 - 08/2006
3	Eosinophilia 07/2011 - 01/2008
3	Rheumatoid Arthritis 01/2010 - 04/2008
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2009 - 04/2008
3	Acute Liver Failure (Fulminant Hepatic Failure) 02/2009 - 06/2002
3	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 11/2005 - 06/2002
3	Pancreatitis 08/2005 - 06/2002
2	Dyskinesias (Dyskinesia) 10/2021 - 09/2017
2	Parkinson Disease (Parkinson's Disease) 10/2021 - 01/2018
2	Thymoma (Thymic Carcinoma) 01/2021 - 01/2017
2	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) 01/2021 - 03/2016
2	Ulcerative Colitis 12/2020 - 01/2017
2	Respiratory Insufficiency (Respiratory Failure) 11/2019 - 04/2012
2	Fibrosis (Cirrhosis) 01/2019 - 11/2012
2	Optic Neuritis (Retrobulbar Neuritis) 10/2017 - 03/2016
2	Neuromyelitis Optica (Devic's Disease) 10/2017 - 09/2015
2	Cleft Palate (Palate, Cleft) 08/2015 - 01/2015
2	Disease Progression 12/2014 - 01/2010
2	Acute Lung Injury 03/2013 - 10/2004
2	Edema (Dropsy) 03/2013 - 08/2005
2	Out-of-Hospital Cardiac Arrest 04/2011 - 07/2005
2	Asthma (Bronchial Asthma) 01/2011 - 01/2008
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 04/2010 - 02/2009
2	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2010 - 04/2008
2	Renal Insufficiency (Renal Failure) 12/2009 - 08/2005
2	T-Cell Leukemia (Leukemia, T Cell) 09/2009 - 06/2008
2	Heart Arrest (Cardiac Arrest) 08/2009 - 01/2009
2	Acute Kidney Injury (Acute Renal Failure) 02/2009 - 10/2003
1	Orthostatic Hypotension (Postural Hypotension) 09/2022

Drug/Important Bio-Agent (IBA)

22	CytokinesIBA 01/2017 - 06/2002
13	Prostaglandin D2IBA 12/2020 - 08/2006
11	Interleukin-6 (Interleukin 6)IBA 12/2012 - 08/2005
10	Polymethyl Methacrylate (Sol)IBA 01/2012 - 12/2002
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2009
8	ProstaglandinsIBA 12/2020 - 08/2003
8	Prostaglandins DIBA 01/2019 - 08/2003
6	prostaglandin D2 receptorIBA 01/2019 - 08/2006
5	AntibodiesIBA 01/2021 - 01/2015
4	Immunoglobulin E (IgE)IBA 04/2016 - 08/2006
4	SteroidsIBA 03/2016 - 09/2006
4	InterleukinsIBA 01/2012 - 07/2003
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2010 - 07/2003
3	Pharmaceutical PreparationsIBA 01/2017 - 05/2015
3	AllergensIBA 04/2016 - 01/2008
3	Transcription Factors (Transcription Factor)IBA 08/2015 - 03/2014
3	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 12/2014 - 08/2006
3	EndotoxinsIBA 03/2013 - 12/2002
3	Biomarkers (Surrogate Marker)IBA 01/2013 - 10/2009
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 08/2010 - 12/2009
2	Levodopa (L Dopa)FDA LinkGeneric 10/2021 - 09/2017
2	Zonisamide (Zonegran)FDA LinkGeneric 10/2021 - 09/2017
2	Telomerase (Telomerase Reverse Transcriptase)IBA 07/2021 - 06/2008
2	Glycine Receptors (Glycine Receptor)IBA 01/2021 - 01/2017
2	Niacin (Nicotinic Acid)FDA LinkGeneric 12/2020 - 01/2017
2	prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA 01/2019 - 01/2014
2	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2018 - 01/2013
2	Messenger RNA (mRNA)IBA 09/2017 - 06/2008
2	EnzymesIBA 11/2016 - 10/2009
2	Prednisolone (Predate)FDA LinkGeneric 03/2016 - 01/2010
2	ramatrobanIBA 05/2015 - 02/2014
2	LipopolysaccharidesIBA 05/2015 - 02/2014
2	Therapeutic UsesIBA 10/2013 - 01/2010
2	Interleukin-2 (IL2)IBA 10/2013 - 08/2013
2	Interleukin-4 (Interleukin 4)IBA 11/2012 - 04/2008
2	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2012 - 04/2008
2	Lactic Acid (Lactate)FDA LinkGeneric 04/2011 - 05/2008
2	Interleukin-5 (Interleukin 5)IBA 02/2011 - 04/2008
2	Rituximab (Mabthera)FDA Link 01/2010 - 04/2008
2	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2010 - 12/2002
2	DNA (Deoxyribonucleic Acid)IBA 09/2009 - 04/2009
2	thiamine triphosphorate (TTP)IBA 04/2009 - 06/2008
1	hydroxide ionIBA 09/2022

Therapy/Procedure

16	Therapeutics 12/2021 - 04/2002
15	Hemodiafiltration 01/2014 - 06/2002
5	Critical Care (Surgical Intensive Care) 01/2012 - 06/2002
4	Artificial Liver (Bioartificial Liver) 02/2009 - 06/2002
3	Punctures 06/2012 - 12/2011
3	Ligation 06/2012 - 12/2011
2	Drug Therapy (Chemotherapy) 07/2021 - 02/2009
2	Oral Administration 03/2016 - 11/2012
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 12/2014 - 01/2014
2	Denervation 02/2014 - 03/2006
2	Mechanical Ventilators (Ventilator) 04/2012 - 02/2006
2	Hemoperfusion 01/2012 - 01/2010
2	Hemofiltration 01/2012 - 01/2010
2	Renal Dialysis (Hemodialysis) 12/2009 - 01/2004
2	Cardiopulmonary Resuscitation (CPR) 08/2009 - 01/2009
2	Renal Replacement Therapy (Therapies, Renal Replacement) 02/2009 - 10/2003
2	Plasma Exchange 01/2005 - 06/2002